Arndt Siekmann’s research aims to understand how arteries and veins form during embryonic development and tissue regeneration and how blood vessels obtain their correct sizes. This is important to ensure the proper distribution of blood flow to all organs. Failure in these processes can lead to human disease, such as arterio-venous malformations. To obtain insights into these questions, the Siekmann lab utilizes genetic zebrafish models that mimic human disease conditions.
Arndt Siekmann studied Biology at the Albert-Ludwigs University in Freiburg im Breisgau and obtained his PhD degree from the University of Technology, Dresden and the Max Planck Institute of Molecular Cell Biology and Genetics working with Prof. Michael Brand. He then joined the laboratory of Dr. Nathan Lawson at the University of Massachusetts Medical School in Worcester, MA for his postdoctoral work. In 2008, he was recruited to the Max Planck Institute for Molecular Biomedicine in Münster as a Junior Research Group Leader. Since 2018, Dr. Siekmann is an Associate Professor at the Perelman School of Medicine at the University of Pennsylvania.